Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233083 | 0.91 | CYP19A1 (0.74) | CYP19A1STS | |
| SCHEMBL2060379 | 0.88 | CYP19A1 (0.73) | CYP19A1STS | |
| SCHEMBL2060244 | 0.85 | CYP19A1 (0.77) | CYP19A1STS | |
| SCHEMBL14426837 | 0.85 | CYP19A1 (1.00) | CYP19A1STS | |
| SCHEMBL2060092 | 0.85 | CYP19A1 (1.00) | CYP19A1 | |
| SCHEMBL29407197 | 0.83 | CYP19A1 (1.00) | CYP19A1STS | |
| SCHEMBL10062739 | 0.83 | CYP19A1 (1.00) | CYP19A1STS | |
| SCHEMBL3235243 | 0.82 | CYP19A1 (1.00) | CYP19A1STS | |
| SCHEMBL2060151 | 0.81 | CYP19A1 (0.72) | CYP19A1STS | |
| SCHEMBL13292778 | 0.81 | CYP19A1 (0.73) | CYP19A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148415-B2 | Sulfamic acid ester compounds useful in the inhibition of steroid sulphatase activity and aromatase activity | STERIX LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-20070213383-A1 | Sulfamic acid ester compounds useful in the inhibition of steroid sulphatase activity and aromatase activity | STERIX LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
| US-20060241173-A1 | A sulfamate compound, especially a sulfamylated flavone, isoflavone or flavanone, that is an inhibitor of both estrone sulfatase activity and aromatase activity for treating breast and endometrial cancers | STERIX LTD. | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241173-A1 | A sulfamate compound, especially a sulfamylated flavone, isoflavone or flavanone, that is an inhibitor of both estrone sulfatase activity and aromatase activity for treating breast and endometrial cancers | STS, SULT1E1, CYP19A1 | CYP19A1 3/4885STS 1/4885 |
| US-20070213383-A1 | Sulfamic acid ester compounds useful in the inhibition of steroid sulphatase activity and aromatase activity | STS, SULT1E1, CYP19A1 | CYP19A1 3/4885STS 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.