Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | WDR5 | P61964 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SARM1 | Q6SZW1 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063914 | 0.85 | KMT2A (0.53) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| SCHEMBL3077127 | 0.84 | KMT2A (0.52) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| SCHEMBL3066903 | 0.84 | KMT2A (0.52) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| SCHEMBL27959313 | 0.81 | NPC1 (0.59) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| Dexlansoprazole SCHEMBL1457401 | 0.80 | NPC1 (0.61) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| Lansoprazole SCHEMBL1457400 | 0.80 | NPC1 (0.61) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| Dexlansoprazole SCHEMBL44975 | 0.79 | CYP2C9 (0.63) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| Lansoprazole SCHEMBL1559598 | 0.79 | CYP2C9 (0.63) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| Lansoprazole SCHEMBL22366 | 0.79 | CYP2C9 (0.63) | MAPTCYP2C9ALDH1A1WDR5KMT2A | |
| Lansoprazole SCHEMBL8597994 | 0.79 | CYP2C9 (0.63) | MAPTCYP2C9ALDH1A1WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3646855-B1 | ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR | LOTTE FINE CHEMICAL CO LTD (KR) | 2024-05-01 | — | — | EP | disclosed |
| US-20200155457-A1 | ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR | LOTTE FINE CHEMICAL CO., LTD. (KR) | 2020-05-21 | — | — | US | disclosed |
| EP-3646855-A2 | ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR | LOTTE Fine Chemical Co., Ltd. (KR) | 2020-05-06 | — | — | EP | disclosed |
| CN-110785164-A | Solid preparation composition for oral administration comprising proton pump inhibitor, solid preparation for oral administration comprising the same, and method for producing the same | 乐天精密化学株式会社 | 2020-02-11 | — | — | CN | disclosed |
| WO-2019004770-A2 | ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR | 롯데정밀화학 주식회사 | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155457-A1 | ORAL SOLID PREPARATION COMPOSITION COMPRISING PROTON PUMP INHIBITOR, ORAL SOLID PREPARATION COMPRISING SAME, AND PREPARATION METHOD THEREFOR | ATP6AP1, ATP6V1G1, ATP6V1H | MAPT 3377/4885CYP2C9 670/4885ALDH1A1 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.