Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30192399 | 0.83 | NR1H2 (0.34) | FFAR1NR1H2NR1H3 | |
| SCHEMBL24897012 | 0.83 | NR1H2 (0.34) | FFAR1NR1H2NR1H3 | |
| SCHEMBL20371661 | 0.82 | FFAR1 (0.37) | FFAR1 | |
| SCHEMBL30154016 | 0.80 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL21819814 | 0.79 | FFAR1 (0.35) | FFAR1NR1H2NR1H3 | |
| SCHEMBL26254927 | 0.79 | KLKB1 (0.37) | FFAR1NR1H2NR1H3 | |
| SCHEMBL22405990 | 0.78 | FFAR1 (0.34) | FFAR1 | |
| SCHEMBL21940571 | 0.77 | LRRK2 (0.39) | FFAR1 | |
| SCHEMBL15723800 | 0.77 | LRRK2 (0.33) | FFAR1NR1H2NR1H3 | |
| SCHEMBL25239415 | 0.76 | CYP1A2 (0.35) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |
| EP-3423445-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | Galapagos NV (BE) | 2019-01-09 | — | — | EP | disclosed |