Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 6/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399490 | 0.84 | ERN1 (0.37) | CHRM5CHKACCR1CCR5CCR8 | |
| SCHEMBL29954471 | 0.84 | ERN1 (0.37) | CHRM5CHKACCR1CCR5CCR8 | |
| SCHEMBL9000508 | 0.76 | CCNC (0.35) | CHRM5CHKAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2600757 | 0.73 | KMT2A (0.46) | CCR1CCR5CCR8CCNT1CDK9 | |
| SCHEMBL16701005 | 0.73 | CHRM5 (0.46) | CHRM5CHKACDK9CYP2A6MAPT | |
| SCHEMBL29955436 | 0.73 | KMT2A (0.46) | CCR1CCR5CCR8CCNT1CDK9 | |
| SCHEMBL4072497 | 0.73 | KDM4C (0.34) | ERN1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL29543569 | 0.72 | — | — | |
| SCHEMBL2458188 | 0.72 | — | — | |
| SCHEMBL1501841 | 0.72 | SLC22A12 (0.31) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006291-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |