Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 4/20 | 0.46 |
| ▸ | GLS2 | Q9UI32 | 4/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NAT1 | P18440 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557103 | 0.86 | PTPN1 (0.56) | HPGDMAOAMAOBMEN1TTR | |
| SCHEMBL7557643 | 0.85 | GSK3B (0.51) | PIM1PIM2AKR1B1HPGDMEN1 | |
| SCHEMBL30977001 | 0.76 | NPC1 (0.58) | HPGDMEN1KMT2A | |
| SCHEMBL30343486 | 0.74 | MEN1 (0.61) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1249881 | 0.74 | MEN1 (0.61) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1249878 | 0.74 | MEN1 (0.61) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL2422392 | 0.74 | MEN1 (0.61) | PIM1PIM2PIM3AKR1B1HPGD | |
| SCHEMBL1249365 | 0.73 | PTPN1 (0.69) | HPGDMAOAMAOBMEN1TTR | |
| SCHEMBL12891965 | 0.73 | PTPN1 (0.69) | HPGDMAOAMAOBMEN1TTR | |
| SCHEMBL1249362 | 0.73 | PTPN1 (0.69) | HPGDMAOAMAOBMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006359-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-01-03 | — | — | WO | disclosed |