Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 7/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20616364 | 0.93 | F10 (0.49) | KDM4EPKMF10F2PLG | |
| SCHEMBL20616361 | 0.83 | KDM4E (0.51) | KDM4EPKMKMT2AF10AR | |
| SCHEMBL20615820 | 0.83 | F10 (0.48) | KDM4EPKMGRIN2BKMT2AF10 | |
| SCHEMBL20616368 | 0.81 | KDM4E (0.53) | KDM4EPKMKMT2AF10AR | |
| SCHEMBL20615642 | 0.81 | IDO1 (0.49) | GRIN2B | |
| SCHEMBL20601051 | 0.81 | IDO1 (0.49) | GRIN2B | |
| SCHEMBL20615754 | 0.81 | KDM4E (0.50) | KDM4EPKMF10F2PLG | |
| SCHEMBL20615649 | 0.79 | KDM4E (0.60) | KDM4EPKMKMT2AF2PLG | |
| SCHEMBL20615646 | 0.76 | KDM4E (0.79) | KDM4EPKMKMT2AF2PLG | |
| SCHEMBL20616363 | 0.75 | IDO1 (0.53) | ALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019003141-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-03 | — | — | WO | disclosed |