Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258082 | 0.92 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC6EP300 | |
| SCHEMBL20618506 | 0.90 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC6MAPK1 | |
| SCHEMBL8251860 | 0.78 | F10 (0.46) | HDAC3HDAC4HDAC1HDAC6MAPK1 | |
| SCHEMBL20618505 | 0.77 | SMN1; SMN2 (0.44) | MAPK1F10HPGDTSHR | |
| SCHEMBL20601550 | 0.77 | SMN1; SMN2 (0.44) | MAPK1F10HPGDTSHR | |
| SCHEMBL18838280 | 0.77 | CACNA1I (0.62) | HDAC3HDAC4HDAC1HDAC6MAPK1 | |
| SCHEMBL1106552 | 0.77 | F10 (0.47) | F10 | |
| SCHEMBL8259083 | 0.77 | MAPK1 (0.47) | MAPK1F10HPGDTSHR | |
| SCHEMBL8257982 | 0.77 | GAA (0.52) | HDAC3HDAC4HDAC1HDAC6EP300 | |
| Hydrochloric Acid SCHEMBL20601475 | 0.76 | SMN1; SMN2 (0.43) | MAPK1F10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019003141-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-03 | — | — | WO | disclosed |