⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464279 | 0.82 | — | — | |
| SCHEMBL21916221 | 0.81 | — | — | |
| SCHEMBL19523558 | 0.81 | — | — | |
| SCHEMBL12176981 | 0.81 | — | — | |
| SCHEMBL23693903 | 0.79 | — | — | |
| SCHEMBL13460867 | 0.79 | GRM4 (0.32) | — | |
| SCHEMBL14366032 | 0.79 | GRM4 (0.32) | — | |
| SCHEMBL27410335 | 0.79 | — | — | |
| SCHEMBL24533281 | 0.79 | — | — | |
| SCHEMBL20881890 | 0.78 | CYP2D6 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11065340-B2 | Polyoxazoline antibody drug conjugates | SERINA THERAPEUTICS, INC. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20190000985-A1 | Polyoxazoline Anitbody Drug Conjugates | SERINA THERAPEUTICS (AL), INC. | 2019-01-03 | — | — | US | disclosed |