SCHEMBL206183

SCHEMBL206183

COC1=NC(C(C)C)C(OC)=NC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369237 1.00
SCHEMBL15341654 0.81
SCHEMBL12241744 0.81
SCHEMBL9604976 0.81
SCHEMBL10200821 0.75
SCHEMBL2808933 0.73
SCHEMBL1770651 0.73
SCHEMBL22984154 0.69
SCHEMBL20055507 0.69
SCHEMBL12444210 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013111158-A2 PROCESS FOR THE PREPARATION OF DPP-IV INHIBITOR MSN LABORATORIES LIMITED (IN) 2013-08-01 WO claimed
WO-2026103846-A1 CYCLIC COMPOUND AND PREPARATION THEREFOR AND PHARMACEUTICAL USE THEREOF 山东先声再明生物制药有限公司 2026-05-21 WO disclosed
EP-4558507-B1 MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN LA ROCHE (CH) 2026-04-29 EP disclosed
US-20260098060-A1 MACROCYCLIC CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2026-04-09 US disclosed
US-20260070945-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2026-03-12 US disclosed
WO-2026041636-A1 MACROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER F. HOFFMANN-LA ROCHE AG (CH) 2026-02-26 WO disclosed
EP-4696316-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-02-18 EP disclosed
US-20260042740-A1 RAS INHIBITORS REVOLUTION MEDICINES INC (US) 2026-02-12 US disclosed
EP-4054719-B1 RAS INHIBITORS REVOLUTION MEDICINES INC (US) 2026-02-11 EP disclosed
EP-4688156-A1 LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS Janssen Pharmaceutica NV (BE) 2026-02-11 EP disclosed
US-5610141-A CELL DIVISION STIMULANT NYCOMED IMAGING AS (NO) 1997-03-11 US disclosed
US-5559111-A HYPOTENSIVE AGENTS; RENIN INHIBITORS; Aliskiren CIBA-GEIGY CORPORATION (US) 1996-09-24 US disclosed
EP-0673388-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY NYCOMED IMAGING AS (NO) 1995-09-27 EP disclosed
EP-0643725-A1 SINGLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY NYCOMED IMAGING AS (NO) 1995-03-22 EP disclosed
EP-0624163-A1 CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION Smithkline Beecham Farmaceutici S.p.A. (IT) 1994-11-17 EP disclosed
CN-1086221-A Peptide compounds HAFSLUND NYCOMED AS (NO) 1994-05-04 CN disclosed
WO-1993024524-A1 SINGLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY HAFSLUND NYCOMED AS (NO) 1993-12-09 WO disclosed
WO-1993024523-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY HAFSLUND NYCOMED AS (NO) 1993-12-09 WO disclosed
WO-1993015106-A1 CYCLIC CALCITONINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) 1993-08-05 WO disclosed
US-4847287-A Pure enantiomers of 4,5-disubstituted gamma-butyrolactams, and their use as antiamnestic agents BAYER AG (DE) 1989-07-11 US disclosed