Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128830 | 0.98 | — | — | |
| SCHEMBL1191814 | 0.91 | — | — | |
| SCHEMBL1192014 | 0.91 | — | — | |
| SCHEMBL63653 | 0.91 | — | — | |
| SCHEMBL13410720 | 0.84 | — | — | |
| SCHEMBL21429861 | 0.77 | — | — | |
| SCHEMBL15368481 | 0.77 | NPC1 (0.39) | HPGDHTTKMT2ASMN1; SMN2 | |
| SCHEMBL11060437 | 0.77 | HPGD (0.45) | HPGDHTTKMT2AUSP2SMN1; SMN2 | |
| SCHEMBL9684500 | 0.77 | KMT2A (0.42) | HPGDHTTKMT2AMEN1USP2 | |
| SCHEMBL18226082 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |