Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20622113 | 0.84 | CNR2 (0.47) | CNR2RPS6KB1PKMAURKACNR1 | |
| SCHEMBL20621895 | 0.83 | CNR2 (0.47) | CNR2RPS6KB1PKMAURKACNR1 | |
| SCHEMBL20621869 | 0.81 | HAVCR2 (0.42) | RPS6KB1PTPN11 | |
| SCHEMBL20600383 | 0.79 | CNR2 (0.38) | CNR2PKMCNR1MEN1KMT2A | |
| SCHEMBL29438254 | 0.79 | CNR2 (0.38) | CNR2PKMCNR1MEN1KMT2A | |
| SCHEMBL20621754 | 0.77 | PTPN11 (0.39) | CNR2RPS6KB1PTPN11 | |
| SCHEMBL23531192 | 0.75 | CNR2 (0.53) | CNR2CNR1PTPN11HTR2C | |
| SCHEMBL29834268 | 0.75 | CNR2 (0.53) | CNR2CNR1PTPN11HTR2C | |
| SCHEMBL20600323 | 0.74 | CNR2 (0.47) | CNR2PKMCNR1MEN1KMT2A | |
| SCHEMBL30824248 | 0.74 | CNR2 (0.47) | CNR2PKMCNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019002132-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |