Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.54 |
| ▸ | SRC | P12931 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627063 | 0.97 | FGFR1 (0.55) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL20627054 | 0.88 | FGFR1 (0.57) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL19350830 | 0.84 | FGFR1 (0.60) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL20603995 | 0.82 | FGFR1 (0.55) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL19350832 | 0.82 | FGFR1 (0.55) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL30419173 | 0.81 | FGFR1 (0.61) | FGFR1SRCALDH1A1MAPTMIF | |
| SCHEMBL19350822 | 0.81 | FGFR1 (0.61) | FGFR1SRCALDH1A1MAPTMIF | |
| SCHEMBL20603931 | 0.79 | FGFR1 (0.56) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL20603933 | 0.79 | FGFR1 (0.56) | FGFR1SRCALDH1A1MAPTTP53 | |
| SCHEMBL19350828 | 0.79 | FGFR1 (0.56) | FGFR1SRCALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |