Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739874 | 0.92 | TTK (1.00) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20627726 | 0.86 | TTK (0.72) | TTKCYP3A4 | |
| SCHEMBL20627911 | 0.86 | TTK (0.64) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17190217 | 0.86 | TTK (0.89) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15739909 | 0.85 | TTK (0.88) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15739897 | 0.85 | TTK (0.87) | TTKCYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL17091561 | 0.84 | TTK (0.86) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17182956 | 0.84 | TTK (0.86) | TTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20627129 | 0.84 | TTK (0.74) | TTKCYP3A4 | |
| SCHEMBL20627908 | 0.84 | TTK (0.86) | TTKCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920181-B1 | PYRAZOLOPYRIMIDINE COMPOUNDS | UNIV HEALTH NETWORK (CA) | 2019-01-09 | — | — | EP | disclosed |