SCHEMBL20627490

SCHEMBL20627490

[O-][S+](c1ccccc1-c1ccc(-c2cnc3[nH]ccc3n2)c(F)c1)N1CCCC1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.64
FEN1 P39748 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20627322 0.99 ALOX5AP (0.64) ALOX5APFEN1
SCHEMBL20627321 0.92 ALOX5AP (0.69) ALOX5APFEN1
SCHEMBL20626937 0.90 ALOX5AP (0.66) ALOX5APFEN1
SCHEMBL20626930 0.84 ALOX5AP (0.67) ALOX5APFEN1
SCHEMBL20626929 0.83 ALOX5AP (0.68) ALOX5APFEN1
SCHEMBL20627447 0.82 ALOX5AP (0.64) ALOX5APFEN1
SCHEMBL21089106 0.80 ALOX5AP (0.66) ALOX5APFEN1
SCHEMBL21088863 0.79 ALOX5AP (0.60) ALOX5APFEN1
SCHEMBL20626920 0.79 FEN1 (0.67) ALOX5APFEN1
SCHEMBL20627143 0.78 ALOX5AP (0.72) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3495359-A1 FLAP MODULATORS Janssen Pharmaceutica NV (BE) 2019-06-12 EP disclosed
EP-3070085-B1 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2019-01-09 EP disclosed