Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 5/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904932 | 0.96 | POLB (0.47) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL17844042 | 0.96 | POLB (0.47) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL17858044 | 0.92 | POLB (0.46) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL29904941 | 0.92 | POLB (0.46) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL17844202 | 0.92 | POLB (0.46) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL17844129 | 0.92 | POLB (0.45) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL29904930 | 0.92 | POLB (0.45) | POLBBRD4GRM2DRD2DRD4 | |
| SCHEMBL29431598 | 0.89 | POLB (0.52) | POLBCRHR1PDE10AEGLN1 | |
| SCHEMBL14677239 | 0.89 | POLB (0.52) | POLBCRHR1PDE10AEGLN1 | |
| SCHEMBL21586180 | 0.89 | POLB (0.39) | POLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194394-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-09 | — | — | EP | disclosed |