Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628371 | 0.96 | POLB (0.39) | POLB | |
| SCHEMBL20267583 | 0.96 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL30122217 | 0.96 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL22036956 | 0.93 | POLB (0.41) | POLB | |
| SCHEMBL21590020 | 0.90 | POLB (0.35) | POLB | |
| SCHEMBL29748659 | 0.86 | POLB (0.30) | POLB | |
| SCHEMBL22038281 | 0.86 | POLB (0.30) | POLB | |
| SCHEMBL20276082 | 0.85 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL30122185 | 0.85 | CYP1A2 (0.31) | CYP1A2 | |
| SCHEMBL14677239 | 0.84 | POLB (0.52) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194394-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-09 | — | — | EP | disclosed |