Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 8/20 | 0.53 |
| ▸ | DCLK1 | O15075 | 5/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.47 |
| ▸ | PIK3C2G | O75747 | 8/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.47 |
| ▸ | AURKA | O14965 | 4/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | STK3 | Q13188 | 1/20 | 0.44 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21937663 | 0.83 | STK3 (0.64) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL20628289 | 0.79 | PIK3CG (0.75) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL20628288 | 0.72 | PIK3CG (0.71) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL20628569 | 0.72 | STK3 (0.64) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL20628529 | 0.70 | PIK3CD (0.68) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL619880 | 0.69 | MAPK7 (1.00) | MAPK7DCLK1LRRK2BRD4 | |
| SCHEMBL18371573 | 0.69 | PIK3CG (0.83) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL20628532 | 0.68 | PIK3CG (0.85) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL24687303 | 0.67 | PIK3CG (0.75) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG | |
| SCHEMBL20628502 | 0.67 | PIK3CG (0.75) | MAPK7DCLK1PIK3CDPIK3C2GPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424929-A1 | PYRIMIDINE SEVEN-MEMBERED-RING COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USES THEREOF | Anhui New Star Pharmaceutical Development Co., Ltd (CN) | 2019-01-09 | — | — | EP | disclosed |