Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20629340 | 0.90 | HDAC6 (0.48) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20629290 | 0.83 | HDAC6 (0.58) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20635578 | 0.83 | HDAC6 (0.58) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL22487712 | 0.82 | HDAC2 (0.55) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20629485 | 0.81 | HDAC6 (0.69) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20629250 | 0.81 | HDAC6 (0.57) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL20605308 | 0.81 | HDAC6 (0.70) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20629487 | 0.80 | HDAC2 (0.54) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20629341 | 0.79 | HDAC6 (0.60) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL20635874 | 0.79 | HDAC6 (0.48) | HDAC6HDAC2HDAC8HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019007836-A1 | NOVEL HDAC6 INHIBITORS, WITH IMPROVED SOLUBILITY AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2019-01-10 | — | — | WO | disclosed |
| EP-3424925-A1 | NOVEL HDAC6 INHIBITORS, WITH IMPROVED SOLUBILITY AND THEIR USES | Universität Regensburg (DE) | 2019-01-09 | — | — | EP | disclosed |