Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 12/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18771733 | 1.00 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18771738 | 1.00 | CHRM2 (0.32) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7677570 | 0.87 | ATM (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7677569 | 0.87 | ATM (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19083908 | 0.87 | ATM (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7677574 | 0.87 | ATM (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Butane SCHEMBL7678465 | 0.84 | MEN1 (0.33) | MEN1TSHRHTTKMT2A | |
| SCHEMBL18771916 | 0.82 | DPP4 (0.31) | — | |
| SCHEMBL20629229 | 0.82 | DPP4 (0.31) | — | |
| SCHEMBL18771443 | 0.82 | DPP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159345-B1 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES INC (US) | 2019-01-09 | — | — | EP | disclosed |