Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | ACACB | O00763 | 4/20 | 0.49 |
| ▸ | ACACA | Q13085 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10121188 | 0.94 | KMT2A (0.68) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL1445917 | 0.90 | HPGD (0.58) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL28799882 | 0.85 | KMT2A (0.66) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL20689737 | 0.84 | KMT2A (0.49) | KMT2APARP10MAPTRAB9APNLIP | |
| SCHEMBL22548771 | 0.83 | PARP10 (0.61) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL2625197 | 0.83 | BCL2 (0.61) | PARP10HPGDMAPTRAB9APOLB | |
| SCHEMBL13687470 | 0.83 | PARP10 (0.58) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL13203385 | 0.83 | HPGD (0.73) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL10869658 | 0.81 | HPGD (0.50) | KMT2APARP10HPGDMAPTRAB9A | |
| SCHEMBL10398826 | 0.81 | KMT2A (0.61) | KMT2APARP10ACACBACACAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |