Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.91 |
| ▸ | PIM3 | Q86V86 | 20/20 | 0.91 |
| ▸ | PIM2 | Q9P1W9 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588201 | 0.96 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL16588119 | 0.96 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL16579636 | 0.89 | PIM1 (0.87) | PIM1PIM3PIM2 | |
| SCHEMBL16579750 | 0.89 | PIM1 (0.87) | PIM1PIM3PIM2 | |
| SCHEMBL15588853 | 0.88 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL16588163 | 0.88 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL9608697 | 0.85 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL3225552 | 0.85 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL9608655 | 0.85 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL9608938 | 0.85 | PIM1 (1.00) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861585-B1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-01-09 | — | — | EP | disclosed |