Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24266959 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL31735253 | 0.78 | USP2 (0.37) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL18588199 | 0.75 | NR1H2 (0.44) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL25273157 | 0.75 | USP2 (0.39) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL17951421 | 0.74 | USP2 (0.33) | USP2SMN1; SMN2EPHX1NR1H2EPHX2 | |
| SCHEMBL31735300 | 0.73 | USP2 (0.38) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL25270241 | 0.71 | MEN1 (0.45) | USP2SMN1; SMN2NR1H2GPR119 | |
| SCHEMBL24906857 | 0.70 | NR1H2 (0.45) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL22022990 | 0.70 | NR1H2 (0.47) | USP2SMN1; SMN2EPHX1RORCNR1H2 | |
| SCHEMBL25224177 | 0.70 | USP2 (0.37) | USP2SMN1; SMN2RORCNR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019009370-A1 | AMIDE DERIVATIVE | 大日本住友製薬株式会社 | 2019-01-10 | — | — | WO | disclosed |