SCHEMBL2063385

SCHEMBL2063385

O=C(O)Cc1c(C(=O)N2CCC(Oc3ccc(Cl)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2064119 0.93 CNR1 (1.00) CNR1
SCHEMBL2065373 0.92 CNR1 (0.92) CNR1
SCHEMBL6123611 0.92 CNR1 (1.00) CNR1
SCHEMBL2063738 0.90 CNR1 (1.00) CNR1
SCHEMBL2064953 0.89 CNR1 (0.80) CNR1
SCHEMBL2063268 0.88 CNR1 (0.86) CNR1
SCHEMBL2064184 0.88 CNR1 (0.80) CNR1
SCHEMBL2065249 0.88 CNR1 (0.92) CNR1
SCHEMBL2064276 0.88 CNR1 (0.89) CNR1
SCHEMBL2063405 0.87 CNR1 (0.77) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121659-B1 MODULATORS OF CB1 RECEPTORS 7TM PHARMA AS (DK) 2013-05-15 EP disclosed
US-8148404-B2 Modulators of CB1 receptors 7TM PHARMA A/S (DK) 2012-04-03 US disclosed
US-20100144701-A1 Modulators of CB1 Receptors 7TM PHARMA A/S (DK) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144701-A1 Modulators of CB1 Receptors CNR1, CNR2, GPR6 CNR1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.