Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.70 |
| ▸ | KIT | P10721 | 16/20 | 0.70 |
| ▸ | ABL2 | P42684 | 13/20 | 0.70 |
| ▸ | BCR | P11274 | 7/20 | 0.70 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.70 |
| ▸ | PLK4 | O00444 | 1/20 | 0.70 |
| ▸ | DDX3X | O00571 | 1/20 | 0.70 |
| ▸ | GAK | O14976 | 1/20 | 0.70 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.70 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ALB | P02768 | 1/20 | 0.70 |
| ▸ | RAF1 | P04049 | 1/20 | 0.70 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635552 | 0.95 | ABL1 (0.70) | ABL1KITABL2BCRPDGFRA | |
| Iodide SCHEMBL15632996 | 0.87 | ABL1 (0.69) | ABL1KITABL2BCRPDGFRA | |
| SCHEMBL18210972 | 0.87 | ABL1 (0.69) | ABL1KITABL2BCRPDGFRA | |
| Iodide SCHEMBL15632994 | 0.87 | ABL1 (0.69) | ABL1KITABL2BCRPDGFRA | |
| Iodide SCHEMBL15632995 | 0.87 | ABL1 (0.68) | ABL1KITABL2BCRPDGFRA | |
| Iodide SCHEMBL15632993 | 0.87 | ABL1 (0.68) | ABL1KITABL2BCRPDGFRA | |
| SCHEMBL30752396 | 0.87 | ABL1 (0.78) | ABL1KITABL2BCRPDGFRA | |
| SCHEMBL18210973 | 0.87 | ABL1 (0.78) | ABL1KITABL2BCRPDGFRA | |
| SCHEMBL3061037 | 0.87 | ABL1 (0.78) | ABL1KITABL2BCRPDGFRA | |
| SCHEMBL15636695 | 0.86 | ABL1 (0.66) | ABL1KITABL2BCRPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141459-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141460-A2 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2019008441-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2019-01-10 | — | — | WO | disclosed |