Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631940 | 0.89 | TSHR (0.38) | TSHR | |
| SCHEMBL22036016 | 0.85 | TSHR (0.34) | TSHR | |
| SCHEMBL21139410 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL21996385 | 0.79 | TSHR (0.38) | TSHR | |
| SCHEMBL18199948 | 0.77 | TSHR (0.30) | TSHR | |
| SCHEMBL21954078 | 0.73 | TSHR (0.32) | TSHR | |
| SCHEMBL8657754 | 0.71 | TSHR (0.62) | TSHR | |
| SCHEMBL17089236 | 0.69 | TSHR (0.43) | TSHR | |
| SCHEMBL9258518 | 0.69 | TSHR (0.43) | TSHR | |
| SCHEMBL10088113 | 0.69 | TSHR (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169924-A2 | SYNTHESIS OF HALICHONDRINS | President And Fellows Of Harvard College (US) | 2023-04-26 | — | — | EP | disclosed |
| EP-3649135-B1 | SYNTHESIS OF HALICHONDRINS | HARVARD COLLEGE (US) | 2022-12-28 | — | — | EP | disclosed |
| WO-2019010363-A1 | SYNTHESIS OF HALICHONDRINS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |