Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.52 |
| ▸ | HTR2C | P28335 | 15/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16531756 | 0.89 | HTR2A (0.51) | HTR2AHTR2C | |
| SCHEMBL884323 | 0.83 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL16531665 | 0.81 | HTR2A (0.52) | HTR2AHTR2C | |
| SCHEMBL885517 | 0.81 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL885433 | 0.81 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL886768 | 0.79 | HTR2A (0.53) | HTR2AHTR2C | |
| SCHEMBL10284609 | 0.78 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL884236 | 0.78 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL885563 | 0.77 | HTR2A (0.55) | HTR2AHTR2C | |
| SCHEMBL10249246 | 0.77 | HTR2A (0.55) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148417-B2 | Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2012-04-03 | — | — | US | disclosed |