SCHEMBL20643154

SCHEMBL20643154

C=CCOc1c(C2CC(OCc3ccccc3)CC(COCc3ccccc3)O2)cc(Cc2ccc(OCC)cc2)c(Cl)c1Br

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.38
SLC5A1 P13866 10/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20643039 0.90 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL20643046 0.89 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL20643036 0.89 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL20643034 0.87 SLC5A2 (0.42) SLC5A2SLC5A1
SCHEMBL20643017 0.86 SLC5A2 (0.45) SLC5A2SLC5A1
SCHEMBL20643055 0.85 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL20643045 0.85 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL20643056 0.84 SLC5A2 (0.37) SLC5A2SLC5A1
SCHEMBL20643033 0.84 SLC5A2 (0.33) SLC5A2SLC5A1
SCHEMBL20643051 0.84 SLC5A2 (0.40) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714032-B1 NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS GREEN CROSS CORP (KR) 2019-01-16 EP disclosed