Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.85 |
| ▸ | FGFR3 | P22607 | 16/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15023010 | 0.92 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023627 | 0.92 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023558 | 0.90 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023679 | 0.87 | FGFR1 (0.76) | FGFR1FGFR3 | |
| SCHEMBL15047986 | 0.87 | FGFR1 (0.80) | FGFR1FGFR3 | |
| SCHEMBL15023770 | 0.87 | FGFR1 (0.80) | FGFR1FGFR3 | |
| SCHEMBL15019854 | 0.85 | FGFR1 (0.72) | FGFR1FGFR3 | |
| SCHEMBL15023320 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023094 | 0.81 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15020408 | 0.80 | FGFR1 (0.84) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153745-A1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| US-20190016724-A1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153745-A1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | NR5A2, FGFR1, FGFR3 | FGFR1 2/4885FGFR3 3/4885 |
| US-20190016724-A1 | DISUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND THEIR USE AS FGFR KINASE INHIBITORS | FGFR1, NR5A2, FGFR3 | FGFR1 1/4885FGFR3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.