Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.32 |
| ▸ | MPL | P40238 | 7/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694342 | 0.97 | RARB (0.44) | RARBRARARARGMAPTRAB9A | |
| SCHEMBL22268268 | 0.90 | S1PR1 (0.42) | RARBRARARARGMAPTRAB9A | |
| SCHEMBL17694324 | 0.89 | RARB (0.39) | RARBRARARARGRAB9AKDM4E | |
| SCHEMBL17694315 | 0.87 | RARB (0.40) | RARBRARARARGRAB9AKDM4E | |
| SCHEMBL17694316 | 0.86 | RARB (0.42) | RARBRARARARGRAB9AKDM4E | |
| SCHEMBL17694346 | 0.86 | RARB (0.39) | RARBRARARARGRAB9AKDM4E | |
| SCHEMBL16265324 | 0.86 | RARB (0.52) | RARBRARARARGMAPTRAB9A | |
| SCHEMBL18464808 | 0.85 | NPC1 (0.39) | RARBRAB9AESR1ESR2PCSK9 | |
| SCHEMBL17694321 | 0.85 | RARB (0.39) | RARBRARARARGRAB9AKDM4E | |
| SCHEMBL17694322 | 0.85 | RARB (0.38) | RARBRARARARGRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190016955-A1 | LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | US | disclosed |