Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | POLA1 | P09884 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | POLG | P54098 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065038 | 0.94 | POLA1 (0.36) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL2065464 | 0.93 | POLA1 (0.35) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL14147838 | 0.92 | PDE3A (0.37) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL2064784 | 0.92 | PDE3A (0.37) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL2889203 | 0.91 | PDE3A (0.38) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL16493643 | 0.87 | POLA1 (0.35) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL2065433 | 0.86 | POLA1 (0.35) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL2064244 | 0.86 | — | — | |
| SCHEMBL10062708 | 0.85 | POLA1 (0.36) | PDE3APOLA1PDE4DSLC29A1POLG | |
| SCHEMBL16502047 | 0.85 | POLA1 (0.36) | PDE3APOLA1PDE4DSLC29A1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148349-B2 | Nucleoside cyclic phosphoramidates for the treatment of RNA-dependent RNA viral infection | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2012-04-03 | — | — | US | disclosed |