Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2693 | 0.86 | ITGB1 (0.46) | ITGB1ITGA4PTPN1MMEMYC | |
| SCHEMBL2772 | 0.84 | ITGB1 (0.44) | ITGB1ITGA4PTPN1MMEMYC | |
| SCHEMBL2132 | 0.81 | MYC (0.47) | ITGB1ITGA4PTPN1MMEMYC | |
| SCHEMBL2870 | 0.81 | MYC (0.47) | ITGB1ITGA4PTPN1MMEMYC | |
| SCHEMBL2174 | 0.79 | MYC (0.45) | CA12CA7CA9CA14ITGB1 | |
| SCHEMBL2432 | 0.79 | MYC (0.45) | CA12CA7CA9CA14ITGB1 | |
| SCHEMBL8065614 | 0.79 | MYC (0.45) | CA12CA7CA9CA14ITGB1 | |
| Hydrochloric Acid SCHEMBL3526296 | 0.78 | MYC (0.45) | CA12CA7CA9CA14ITGB1 | |
| Hydrochloric Acid SCHEMBL15663201 | 0.78 | MYC (0.45) | CA12CA7CA9CA14ITGB1 | |
| SCHEMBL7177998 | 0.78 | MME (0.52) | ITGB1ITGA4PTPN1MMEMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |