Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 20/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353595 | 1.00 | CHRM1 (0.49) | CHRM1PDE2APDE11A | |
| SCHEMBL20636655 | 0.94 | CHRM1 (0.53) | CHRM1PDE2APDE11A | |
| SCHEMBL20636651 | 0.90 | CHRM1 (0.55) | CHRM1 | |
| SCHEMBL20636654 | 0.90 | CHRM1 (0.55) | CHRM1 | |
| SCHEMBL20636653 | 0.90 | CHRM1 (0.55) | CHRM1 | |
| SCHEMBL20636628 | 0.89 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL20636636 | 0.89 | CHRM1 (0.57) | CHRM1 | |
| SCHEMBL20636632 | 0.89 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL20636630 | 0.89 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL19353594 | 0.89 | CHRM1 (0.56) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428150-B1 | AROMATIC RING COMPOUND HAVING A CHOLINERGIC MUSCARINE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATOR ACTIVITY | TAKEDA PHARMACEUTICALS CO (JP) | 2023-07-12 | — | — | EP | disclosed |
| EP-3428150-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-01-16 | — | — | EP | disclosed |