Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783979 | 0.85 | APP (0.45) | APPALDH1A1LMNAKMT2AMIF | |
| SCHEMBL16569010 | 0.85 | TYR (0.46) | TYRAPPAKR1C3AKR1C2ALDH1A3 | |
| SCHEMBL8850119 | 0.81 | APP (0.49) | APPADRB2ADRB1ADRB3LMNA | |
| SCHEMBL5215244 | 0.81 | APP (0.49) | APPAKR1C3AKR1C2ADRB2ADRB1 | |
| SCHEMBL1125147 | 0.81 | TYR (0.53) | TYRAKR1C3AKR1C2ALDH1A3ADRB2 | |
| SCHEMBL6349692 | 0.79 | APP (0.58) | APPLMNAKMT2AMAPK1 | |
| SCHEMBL550740 | 0.79 | APP (0.48) | APPADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL4538904 | 0.79 | APP (0.48) | APPALDH1A1LMNAKMT2AMAPK1 | |
| SCHEMBL2289610 | 0.79 | APP (0.47) | APPALDH1A1KMT2ARECQL | |
| SCHEMBL16782694 | 0.79 | APP (0.47) | APPALDH1A1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062884-B1 | Phenylacetic acid derivatives and pharmaceutical composition thereof | FUJI YAKUHIN CO LTD (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-8148421-B2 | Phenylacetic acid derivative | FUJI YAKUHIN CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2062884-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2009-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | PTGS1, PTGER1, PTGDR | TYR 535/4885APP 4410/4885AKR1C3 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.