Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 9/20 | 0.79 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090266 | 0.91 | PTP4A3 (0.85) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2067343 | 0.88 | PTP4A3 (1.00) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2067340 | 0.88 | PTP4A3 (1.00) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2065609 | 0.86 | PTP4A3 (0.77) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2065614 | 0.86 | PTP4A3 (0.77) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL10090227 | 0.85 | PTP4A3 (0.75) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2064654 | 0.85 | PTP4A3 (0.75) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2064655 | 0.85 | PTP4A3 (0.75) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL10090269 | 0.84 | PTP4A3 (1.00) | PTP4A3PTPN1CISD1MEN1KMT2A | |
| SCHEMBL2065002 | 0.84 | PTP4A3 (1.00) | PTP4A3PTPN1CISD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | claimed |