Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.62 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.43 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074050 | 0.82 | P2RY12 (0.53) | P2RY12ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL2065766 | 0.82 | P2RY12 (0.53) | P2RY12ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL5002843 | 0.82 | P2RY12 (0.53) | P2RY12ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL2067079 | 0.81 | P2RY12 (0.73) | P2RY12PGRADORA3CHRM1DRD1 | |
| SCHEMBL2067043 | 0.80 | P2RY12 (0.60) | P2RY12NAE1UBA3 | |
| SCHEMBL5002622 | 0.78 | P2RY12 (0.57) | P2RY12ALDH1A1 | |
| SCHEMBL2066938 | 0.78 | P2RY12 (0.57) | P2RY12ALDH1A1 | |
| Bicarbonate SCHEMBL7509640 | 0.77 | P2RY12 (0.66) | P2RY12CYP2C9 | |
| SCHEMBL2065338 | 0.77 | P2RY12 (1.00) | P2RY12CYP2C9PGRADORA3CHRM1 | |
| Bicarbonate SCHEMBL7510618 | 0.77 | P2RY12 (0.65) | P2RY12NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148385-B2 | Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-03 | — | — | US | claimed |
| US-20080312257-A1 | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-18 | — | — | US | claimed |
| US-8148385-B2 | Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-03 | — | — | US | disclosed |
| US-8148385-B2 | Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-03 | — | — | US | disclosed |
| US-8148385-B2 | Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-04-03 | — | — | US | disclosed |
| US-20080312257-A1 | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-18 | — | — | US | disclosed |
| US-20080312257-A1 | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-18 | — | — | US | disclosed |
| US-20080312257-A1 | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312257-A1 | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists | P2RY12, P2RY1, P2RY2 | P2RY12 1/4885NAE1 1849/4885UBA3 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.