⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905213 | 0.81 | — | — | |
| SCHEMBL857201 | 0.74 | — | — | |
| SCHEMBL23947099 | 0.72 | — | — | |
| SCHEMBL11831696 | 0.70 | — | — | |
| SCHEMBL15577679 | 0.70 | — | — | |
| SCHEMBL31619757 | 0.70 | — | — | |
| SCHEMBL16926831 | 0.70 | — | — | |
| SCHEMBL20595115 | 0.70 | — | — | |
| SCHEMBL23536217 | 0.70 | — | — | |
| SCHEMBL11839854 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250293-A1 | INHIBITORS OF MEK KINASE | MOSAICA MEDICINES, INC. | 2025-08-07 | — | — | US | disclosed |
| EP-4486750-A1 | INHIBITORS OF MEK KINASE | Kinnate Biopharma Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-119137130-A | Inhibitors of MEK kinase | 金耐特生物制药公司 | 2024-12-13 | — | — | CN | disclosed |
| US-12122800-B2 | Inhibitors of MEK kinase | KINNATE BIOPHARMA INC. (US) | 2024-10-22 | — | — | US | disclosed |
| US-20230416286-A1 | INHIBITORS OF MEK KINASE | MOSAICA MEDICINES, INC. | 2023-12-28 | — | — | US | disclosed |
| US-11780862-B2 | Inhibitors of MEK kinase | KINNATE BIOPHARMA INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-11780862-B2 | Inhibitors of MEK kinase | KINNATE BIOPHARMA INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-11780862-B2 | Inhibitors of MEK kinase | KINNATE BIOPHARMA INC. (US) | 2023-10-10 | — | — | US | disclosed |
| WO-2023168203-A1 | INHIBITORS OF MEK KINASE | KINNATE BIOPHARMA INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023168203-A1 | INHIBITORS OF MEK KINASE | KINNATE BIOPHARMA INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20230279033-A1 | INHIBITORS OF MEK KINASE | MOSAICA MEDICINES, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230279033-A1 | INHIBITORS OF MEK KINASE | MOSAICA MEDICINES, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230174544-A1 | NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-20230174544-A1 | NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2023-06-08 | — | — | US | disclosed |
| WO-2021210911-A1 | NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | 주식회사 엘지화학 | 2021-10-21 | — | — | WO | disclosed |
| CN-111032641-A | Substituted 5-cyanoindole compounds and uses thereof | 诺华股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| US-10604502-B2 | Substituted 5-cyanoindole compounds and uses thereof | NOVARTIS AG (CH) | 2020-03-31 | — | — | US | disclosed |
| US-10604502-B2 | Substituted 5-cyanoindole compounds and uses thereof | NOVARTIS AG (CH) | 2020-03-31 | — | — | US | disclosed |
| US-20190023684-A1 | SUBSTITUTED 5-CYANOINDOLE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2019-01-24 | — | — | US | disclosed |
| US-20190023684-A1 | SUBSTITUTED 5-CYANOINDOLE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2019-01-24 | — | — | US | disclosed |