Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066071 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL3250163 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL15260806 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL4947876 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL5665869 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL11966748 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL11966739 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL10535639 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL7351254 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 | |
| SCHEMBL1697602 | 1.00 | HTR2C (0.57) | HTR2CNOD1NAAADGKAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103338743-B | A kind of Cleasing compositions of stiff | SUZHOU YUANSUJI CHEMICAL INDUSTRY Co.,Ltd. (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-103338743-B | A kind of Cleasing compositions of stiff | SUZHOU YUANSUJI CHEMICAL INDUSTRY Co.,Ltd. (CN) | 2016-06-01 | — | — | CN | disclosed |
| EP-1895979-B1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO LTD (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-8147854-B2 | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100112017-A1 | Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| WO-2008032883-A2 | COMPOSITION FOR THE PREPARATION OF COSMETICS, COSMETIC, AND METHOD FOR THE PREPARATION OF WATER-CONTAINING COSMETICS | DOW CORNING TORAY CO., LTD. (JP) | 2008-03-20 | — | — | WO | disclosed |
| EP-1895979-A1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | Dow Corning Toray Co., Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006137576-A1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | H1-0, H1-2, CHRM1 | HTR2C 2047/4885NOD1 2487/4885NAAA 3749/4885 |
| US-20100112017-A1 | Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics | H1-0, DEGS1, MSR1 | HTR2C 866/4885NOD1 2355/4885NAAA 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.