Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676466 | 0.85 | MEN1 (0.49) | MAPTHTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20117112 | 0.85 | MEN1 (0.49) | MAPTHTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20116235 | 0.85 | MEN1 (0.49) | MAPTHTTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20117115 | 0.79 | GRM5 (0.49) | MAPTKMT2ASMN1; SMN2TP53MEN1 | |
| SCHEMBL20117114 | 0.79 | GRM5 (0.49) | MAPTKMT2ASMN1; SMN2TP53MEN1 | |
| SCHEMBL20116255 | 0.79 | GRM5 (0.49) | MAPTKMT2ASMN1; SMN2TP53MEN1 | |
| SCHEMBL20660846 | 0.78 | MAPT (0.61) | MAPTPKMHTTKMT2ASMN1; SMN2 | |
| SCHEMBL20117003 | 0.71 | MAPT (0.56) | MAPTHTTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL30720981 | 0.71 | MAPT (0.56) | MAPTHTTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL20116140 | 0.71 | MAPT (0.56) | MAPTHTTSMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700934-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |