Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 9/20 | 0.73 |
| ▸ | PIM1 | P11309 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.50 |
| ▸ | NAT1 | P18440 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090223 | 1.00 | PTP4A3 (0.73) | PTP4A3PIM1PDE4BGSK3BCISD1 | |
| SCHEMBL2066284 | 1.00 | PTP4A3 (0.73) | PTP4A3PIM1PDE4BGSK3BCISD1 | |
| SCHEMBL2065201 | 0.85 | PTP4A3 (0.81) | PTP4A3PIM1GSK3BCISD1 | |
| SCHEMBL2065204 | 0.85 | PTP4A3 (0.81) | PTP4A3PIM1GSK3BCISD1 | |
| SCHEMBL10090197 | 0.85 | PTP4A3 (0.77) | PTP4A3PIM1GSK3BCISD1 | |
| SCHEMBL2066247 | 0.85 | PTP4A3 (0.77) | PTP4A3PIM1GSK3BCISD1 | |
| SCHEMBL2066245 | 0.85 | PTP4A3 (0.77) | PTP4A3PIM1GSK3BCISD1 | |
| SCHEMBL10090212 | 0.85 | PTP4A3 (1.00) | PTP4A3PIM1GSK3BCISD1KCNH2 | |
| SCHEMBL2066444 | 0.81 | PTP4A3 (0.71) | PTP4A3PIM1PDE4BGSK3BCISD1 | |
| SCHEMBL2066441 | 0.81 | PTP4A3 (0.71) | PTP4A3PIM1PDE4BGSK3BCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | claimed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | claimed |
| US-8148541-B2 | Rhodanine derivatives, a process for the preparation thereof and pharmaceutical composition containing the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042872-A1 | Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same | PTPRR, PTPRG, PTPRS | PTP4A3 28/4885PIM1 2536/4885PDE4B 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.