Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803492 | 1.00 | TSHR (0.57) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL20664401 | 1.00 | TSHR (0.57) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL15706230 | 0.99 | TSHR (0.55) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL3476552 | 0.96 | TSHR (0.51) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL12205511 | 0.96 | TSHR (0.55) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL18503070 | 0.96 | TSHR (0.61) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL13400993 | 0.95 | TSHR (0.59) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL3478277 | 0.93 | TSHR (0.52) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL13400996 | 0.93 | TSHR (0.55) | TSHRHTTMEN1KMT2ATP53 | |
| SCHEMBL21531835 | 0.91 | TSHR (0.43) | TSHRHTTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607451-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |