Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 9/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20327073 | 1.00 | P2RY6 (0.54) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL19862754 | 0.93 | P2RY6 (0.59) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL18126746 | 0.93 | P2RY6 (0.59) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL19546708 | 0.93 | P2RY6 (0.59) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL24043084 | 0.93 | P2RY6 (0.59) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL18538842 | 0.89 | P2RY6 (0.52) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL21763394 | 0.89 | P2RY6 (0.56) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL15989021 | 0.88 | P2RY6 (0.53) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL17577464 | 0.88 | P2RY2 (0.56) | P2RY6P2RY2P2RY14P2RY4 | |
| SCHEMBL24071231 | 0.88 | P2RY2 (0.50) | P2RY6P2RY2P2RY14P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844377-B2 | Two-tailed self-delivering siRNA | UNIVERSITY OF MASSACHUSETTS (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190024082-A1 | TWO-TAILED SELF-DELIVERING SIRNA | UNIVERSITY OF MASSACHUSETTS | 2019-01-24 | — | — | US | disclosed |