Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP10 | P09238 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21553840 | 0.84 | KDM4E (0.44) | KDM4EKMT2ACYP1A2OPRM1LMNA | |
| Hydrochloric Acid SCHEMBL7343047 | 0.82 | KDM4E (0.42) | KDM4EKMT2ACYP1A2OPRM1LMNA | |
| SCHEMBL5110993 | 0.82 | NPSR1 (0.39) | KMT2ACYP1A2LMNANPSR1CYP3A4 | |
| SCHEMBL31693649 | 0.79 | CYP1A2 (0.37) | KDM4EKMT2ACYP1A2OPRM1MMP3 | |
| SCHEMBL4851344 | 0.77 | KDM4E (0.37) | KDM4EKMT2AOPRM1LMNANPSR1 | |
| SCHEMBL853241 | 0.77 | KDM4E (0.37) | KDM4EKMT2AOPRM1LMNANPSR1 | |
| SCHEMBL20669320 | 0.76 | GRM4 (0.39) | KDM4EKMT2ACYP1A2LMNACYP2C19 | |
| Hydrochloric Acid SCHEMBL28563631 | 0.76 | KDM4E (0.36) | KDM4EKMT2AOPRM1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL28563629 | 0.76 | KDM4E (0.36) | KDM4EKMT2AOPRM1LMNANPSR1 | |
| SCHEMBL231396 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656782-B1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN) | 2021-12-22 | — | — | EP | disclosed |
| EP-3656782-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019015644-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2019-01-24 | — | — | WO | disclosed |