⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13009496 | 1.00 | — | — | |
| SCHEMBL14040230 | 1.00 | — | — | |
| Iodide SCHEMBL20854663 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL20877025 | 0.96 | — | — | |
| Bromide SCHEMBL20877214 | 0.96 | — | — | |
| SCHEMBL18485025 | 0.82 | — | — | |
| SCHEMBL21440748 | 0.80 | — | — | |
| SCHEMBL4203556 | 0.78 | — | — | |
| SCHEMBL27488910 | 0.78 | KDM1A (0.30) | — | |
| SCHEMBL4203534 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912373-A | Angiogenesis inhibitor, preparation method and application thereof | 北京康辰药业股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| WO-2025133396-A1 | NOVEL BICYCLO HETEROARYL PARG INHIBITORS | FORX THERAPEUTICS AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| CN-116507625-A | Isochromic amine nerve plasticizer and application thereof | 德力克斯疗法有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-111163765-B | Method for inhibiting conversion of choline to Trimethylamine (TMA) | 宝洁公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115298168-A | Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding | 普罗泰格生物制药公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-112912373-B | Angiogenesis inhibitor, preparation method and application thereof | 北京康辰药业股份有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-113644261-B | Method for modifying ternary cathode material through nano networking, cathode material and lithium ion battery | 万华化学(四川)有限公司 | 2022-08-05 | — | — | CN | disclosed |
| EP-1417186-B1 | HETEROCYCLIC ARYL SULPHONAMIDES | AICURIS GMBH & CO KG (DE) | 2011-03-16 | — | — | EP | disclosed |
| US-20100215652-A1 | NICOTINAMIDE DERIVATES USEFUL AS P38 INHIBITORS | ASTON NICOLA MARY | 2010-08-26 | — | — | US | disclosed |
| US-20100176338-A1 | Composition Comprising Neopentasilane And Method Of Preparing Same | NATA SEMICONDUCTOR MATERIALS CO., LTD. (CN) | 2010-07-15 | — | — | US | disclosed |
| EP-2076558-A1 | COMPOSITION COMPRISING NEOPENTASILANE AND METHOD OF PREPARING SAME | Dow Corning Corporation (US) | 2009-07-08 | — | — | EP | disclosed |
| US-7514456-B2 | Nicotinamide derivatives useful as p38 inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-07 | — | — | US | disclosed |
| EP-1760726-B1 | Conductive paste | SANYO ELECTRIC CO (JP) | 2008-10-22 | — | — | EP | disclosed |
| WO-2008051328-A1 | COMPOSITION COMPRISING NEOPENTASILANE AND METHOD OF PREPARING SAME | DOW CORNING CORPORATION (US) | 2008-05-02 | — | — | WO | disclosed |
| US-20060276516-A1 | Nicotinamide Derivatives Useful as p38 Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-12-07 | — | — | US | disclosed |
| US-20060264479-A1 | Nicotinamide Derivatives Useful as p38 Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-11-23 | — | — | US | disclosed |
| EP-1170281-B1 | 1,1- and 1,2-disubstituted cyclopropanes, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2005-12-21 | — | — | EP | disclosed |