SCHEMBL20676017

SCHEMBL20676017

CC(C)CC(C(=O)O)N1CC(C(=O)O)CC1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.66
POLB P06746 5/20 0.55
KMT2A Q03164 1/20 0.54
RECQL P46063 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALOX15 P16050 1/20 0.41
MME P08473 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28561762 0.86 BRD4 (0.50) MAPTPOLBKMT2ASMN1; SMN2MME
SCHEMBL28561759 0.86 BRD4 (0.50) MAPTPOLBKMT2ASMN1; SMN2MME
SCHEMBL13189284 0.83 SMN1; SMN2 (0.43) MAPTPOLBKMT2ASMN1; SMN2MME
SCHEMBL30282392 0.80 MAPT (1.00) MAPTPOLBKMT2ARECQLSMN1; SMN2
SCHEMBL2164818 0.80 MAPT (1.00) MAPTPOLBKMT2ARECQLSMN1; SMN2
SCHEMBL25209200 0.80 MAPT (1.00) MAPTPOLBKMT2ARECQLSMN1; SMN2
SCHEMBL25227301 0.80 MAPT (1.00) MAPTPOLBKMT2ARECQLSMN1; SMN2
SCHEMBL20676016 0.79 MAPT (0.77) MAPTPOLBKMT2ARECQLSMN1; SMN2
SCHEMBL6535458 0.79 MAPT (0.82) MAPTPOLBKMT2ARECQLSMN1; SMN2
SCHEMBL14990444 0.77 MAPT (0.79) MAPTPOLBKMT2ARECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10738151-B2 Biorenewable, water-degradable polymers and co-polymers UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2020-08-11 US disclosed
US-20190023839-A1 BIORENEWABLE, WATER-DEGRADABLE POLYMERS AND CO-POLYMERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2019-01-24 US disclosed