Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031966 | 1.00 | MEN1 (0.58) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL31040386 | 0.89 | MEN1 (0.65) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL31325605 | 0.89 | MEN1 (0.65) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL26789194 | 0.86 | MEN1 (0.61) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL25353243 | 0.86 | MEN1 (0.69) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL25353238 | 0.86 | MEN1 (0.69) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL29107778 | 0.85 | MEN1 (0.60) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL14535129 | 0.85 | MEN1 (0.60) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL28546640 | 0.84 | MEN1 (0.52) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL16760315 | 0.83 | MEN1 (0.65) | MEN1KMT2AGAATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-3432934-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2019-01-30 | — | — | EP | disclosed |