Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 19/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17871610 | 0.83 | CCR6 (0.47) | CCR6GAA | |
| SCHEMBL1706775 | 0.83 | GAA (0.53) | CCR6GAA | |
| SCHEMBL1706737 | 0.82 | CCR6 (0.68) | CCR6 | |
| SCHEMBL17871639 | 0.80 | CXCR2 (0.48) | CCR6GAA | |
| SCHEMBL1579382 | 0.79 | CXCR2 (0.61) | CCR6 | |
| SCHEMBL20721128 | 0.78 | CCR6 (0.64) | CCR6 | |
| SCHEMBL1579035 | 0.77 | CCR6 (0.53) | CCR6 | |
| SCHEMBL2296860 | 0.76 | CCR6 (0.53) | CCR6 | |
| SCHEMBL14895001 | 0.74 | CCR6 (0.65) | CCR6GAA | |
| SCHEMBL20721260 | 0.73 | CCR6 (0.69) | CCR6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237384-B1 | NOVEL CHEMOKINE CXCR1 AND CXCR2 RECEPTOR ANTAGONIST COMPOUNDS, AND USE THEREOF IN THE TREATMENT OF CHEMOKINE-MEDIATED PATHOLOGIES | GALDERMA RES & DEV (FR) | 2019-01-30 | — | — | EP | claimed |