Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 16/20 | 1.00 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677835 | 0.87 | HSP90AA1 (1.00) | HSP90AA1PDK1 | |
| SCHEMBL20677851 | 0.85 | HSP90AA1 (1.00) | HSP90AA1PDK1 | |
| SCHEMBL19182758 | 0.81 | HSP90AA1 (0.68) | HSP90AA1PDK1HSP90AB1 | |
| SCHEMBL20677841 | 0.78 | HSP90AA1 (1.00) | HSP90AA1PDK1HSP90AB1 | |
| SCHEMBL20677870 | 0.78 | HSP90AA1 (0.78) | HSP90AA1PDK1 | |
| SCHEMBL645589 | 0.78 | HSP90AA1 (0.62) | HSP90AA1PDK1HSP90AB1 | |
| SCHEMBL30474378 | 0.78 | HSP90AA1 (1.00) | HSP90AA1PDK1 | |
| SCHEMBL19182979 | 0.78 | HSP90AA1 (1.00) | HSP90AA1PDK1 | |
| SCHEMBL2081512 | 0.77 | HSP90AA1 (0.61) | HSP90AA1PDK1HSP90AB1 | |
| SCHEMBL30474395 | 0.77 | HSP90AA1 (1.00) | HSP90AA1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661661-A | Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof | 恩科森株式会社 | 2021-04-16 | — | — | CN | claimed |
| CN-108884021-A | Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof | 启明大学校产学协力团 | 2018-11-23 | — | — | CN | claimed |
| CN-108884021-B | Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof | 恩科森株式会社 | 2021-06-01 | — | — | CN | disclosed |
| CN-112661661-A | Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof | 恩科森株式会社 | 2021-04-16 | — | — | CN | disclosed |
| US-10889552-B2 | Dihydroxybenzamide compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof | ONCOZEN CO.. LTD. (KR) | 2021-01-12 | — | — | US | disclosed |
| US-10464907-B2 | Compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof | INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY (KR) | 2019-11-05 | — | — | US | disclosed |
| US-20190031620-A1 | NOVEL COMPOUND HAVING HSP90 INHIBITORY ACTIVITY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MEDICAL USE THEREOF | INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY (KR) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889552-B2 | Dihydroxybenzamide compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885PDK1 1644/4885HSP90AB1 1/4885 |
| US-20190031620-A1 | NOVEL COMPOUND HAVING HSP90 INHIBITORY ACTIVITY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MEDICAL USE THEREOF | HSP90AA1, HSP90AB1, HSP90AB2P | HSP90AA1 1/4885PDK1 1807/4885HSP90AB1 2/4885 |
| US-10464907-B2 | Compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof | HSP90AA1, HSP90AB1, HSP90AB2P | HSP90AA1 1/4885PDK1 1764/4885HSP90AB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.