Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20685200 | 1.00 | IDH1 (0.69) | IDH1 | |
| SCHEMBL19104435 | 1.00 | IDH1 (0.69) | IDH1 | |
| SCHEMBL17009727 | 1.00 | IDH1 (0.69) | IDH1 | |
| SCHEMBL17009724 | 1.00 | IDH1 (0.69) | IDH1 | |
| SCHEMBL17009721 | 1.00 | IDH1 (0.69) | IDH1 | |
| SCHEMBL18477019 | 0.82 | RPS6KB1 (0.55) | IDH1 | |
| SCHEMBL23280137 | 0.82 | IDH1 (1.00) | IDH1 | |
| SCHEMBL18376875 | 0.82 | IDH1 (1.00) | IDH1 | |
| SCHEMBL18376796 | 0.82 | IDH1 (1.00) | IDH1 | |
| SCHEMBL20414992 | 0.82 | IDH1 (1.00) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105209-B1 | BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS | Bayer Pharma AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3105210-B1 | BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS | Bayer Pharma AG (DE) | 2019-01-30 | — | — | EP | disclosed |