Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686615 | 0.93 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL24508635 | 0.91 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL20686565 | 0.87 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL20686558 | 0.85 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL20686576 | 0.83 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL20686575 | 0.83 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL20686559 | 0.83 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL20686562 | 0.83 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL16481683 | 0.83 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL18472783 | 0.83 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903617-B1 | INHIBITORS OF IRAK4 ACTIVITY | MERCK SHARP & DOHME (US) | 2019-01-30 | — | — | EP | disclosed |