⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829242 | 0.59 | — | — | |
| SCHEMBL496676 | 0.58 | — | — | |
| SCHEMBL557663 | 0.58 | KDM4E (0.41) | — | |
| SCHEMBL3233587 | 0.58 | — | — | |
| SCHEMBL10969170 | 0.56 | — | — | |
| SCHEMBL3431562 | 0.54 | — | — | |
| SCHEMBL27333545 | 0.54 | — | — | |
| SCHEMBL3380522 | 0.48 | — | — | |
| SCHEMBL44900 | 0.48 | — | — | |
| SCHEMBL4026843 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438064-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES | Novartis AG (CH) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139731-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE DERIVATIVES | NOVARTIS AG (CH) | 2010-12-09 | — | — | WO | disclosed |